Abstract
The first diastereoselective cycloaddition of a nitrile oxide with a homoallylic alcohol is discussed. The reaction of benzonitrile oxide with the magnesium alkoxides of chiral homoallylic alcohols has been shown to proceed with good diastereoselectivity, favoring the syn isomer of the resulting 2-isoxazoline.
Original language | English (US) |
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Pages (from-to) | 1811-1813 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 44 |
Issue number | 9 |
DOIs | |
State | Published - Feb 24 2003 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry