Diet in vitamin a research

A. Catharine Ross

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Scopus citations


A properly formulated diet is an essential underpinning for all in vivo research. This chapter focuses on the use of diet in retinoid research from two perspectives: human research, in which diet is usually variable and analysis of dietary intake is paramount to interpreting the study's results, and animal (rodent) research, in which diet is imposed as a factor in the experimental design, and the diet consumed is usually monotonous. Many standard rodent diets are nonpurified and the amount of vitamin A in the diet is unknown. Moreover, it is likely to be much higher than expected from the label. By using a well-formulated purified diet with an exact amount of vitamin A, retinoid status in rodents can be closely controlled to create specific physiological conditions that represent the wide range of vitamin A status present in human populations.

Original languageEnglish (US)
Title of host publicationRetinoids
Subtitle of host publicationMethods and Protocols
Number of pages19
StatePublished - 2010

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics


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