TY - JOUR
T1 - Dietary intake and plasma lipid levels
T2 - Lessons from a study of the diet of health conscious groups
AU - Thorogood, M.
AU - Roe, L.
AU - McPherson, K.
AU - Mann, J.
N1 - Funding Information:
We thank Dr Alison Black and Dr Tim Key for their advice. This study has been supported financially by the Cancer Research Campaign, the Imperial Cancer Research Fund, and the Dr Hadwen Trust for Humane Research. The Nibbles nutrient analysis program is copyright of Dr D Yeates.
PY - 1990
Y1 - 1990
N2 - Aim - To re-examine the contentious relation between diet and plasma lipids within a population. Design - Cross sectional sample from a large prospective cohort study of people eating different diets in Britain. Blood samples and diet records collected from subjects. Subjects - Volunteers eating one of four distinct diets - namely, vegans, vegetarians, fish eaters who do not eat meat, and meat eaters. 52 Subjects selected from each group. Methods - Examination of the relation between nutritional intake recorded in a four day dietary record and plasma lipid concentrations of subjects measured in blood sample collected previously. Results - After controlling for age, sex, and body mass index, the correlation between plasma total cholesterol and the Keys score (which includes dietary cholesterol and saturated and polyunsaturated fat) was 0.37 (p < 0.001). The mean saturated fat intake in all groups was low (6-14% of energy), but polyunsaturated fat intake was high, so mean total fat intake was generally above that recommended. A high dietary fibre intake was not associated with high carbohydrate intake. Plasma high density lipoprotein values were not associated with any measure of fat intake, but there was a significant correlation of 0.24 between high density lipoprotein values and alcohol intake. Conclusions - The nature rather than quantity of dietary fat is an important determinant of cholesterol concentrations. Health conscious individuals select a fat modified, rather than a low fat - high carbohydrate diet. National cholesterol lowering dietary advice should be reconsidered.
AB - Aim - To re-examine the contentious relation between diet and plasma lipids within a population. Design - Cross sectional sample from a large prospective cohort study of people eating different diets in Britain. Blood samples and diet records collected from subjects. Subjects - Volunteers eating one of four distinct diets - namely, vegans, vegetarians, fish eaters who do not eat meat, and meat eaters. 52 Subjects selected from each group. Methods - Examination of the relation between nutritional intake recorded in a four day dietary record and plasma lipid concentrations of subjects measured in blood sample collected previously. Results - After controlling for age, sex, and body mass index, the correlation between plasma total cholesterol and the Keys score (which includes dietary cholesterol and saturated and polyunsaturated fat) was 0.37 (p < 0.001). The mean saturated fat intake in all groups was low (6-14% of energy), but polyunsaturated fat intake was high, so mean total fat intake was generally above that recommended. A high dietary fibre intake was not associated with high carbohydrate intake. Plasma high density lipoprotein values were not associated with any measure of fat intake, but there was a significant correlation of 0.24 between high density lipoprotein values and alcohol intake. Conclusions - The nature rather than quantity of dietary fat is an important determinant of cholesterol concentrations. Health conscious individuals select a fat modified, rather than a low fat - high carbohydrate diet. National cholesterol lowering dietary advice should be reconsidered.
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U2 - 10.1136/bmj.300.6735.1297
DO - 10.1136/bmj.300.6735.1297
M3 - Article
C2 - 2369659
AN - SCOPUS:0025289264
SN - 0959-8146
VL - 300
SP - 1297
EP - 1301
JO - British Medical Journal
JF - British Medical Journal
IS - 6735
ER -