TY - JOUR
T1 - Dietary Patterns, Physical Activity, Sleep, and Risk for Dementia and Cognitive Decline
AU - Zhao, Chen
AU - Noble, James M.
AU - Marder, Karen
AU - Hartman, Jacob S.
AU - Gu, Yian
AU - Scarmeas, Nikolaos
N1 - Publisher Copyright:
© 2018, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Purpose of Review: Diet, physical activity, and sleep are three major modifiable lifestyle factors. This selective review examines the evidence for strong and reliable associations between these three lifestyle factors and risk of dementia and cognitive decline, in an effort to assist clinicians with providing more informed answers to the common questions they face from patients. Recent Findings: Certain aspects of nutrition can decrease risk for dementia. Physical activity has also been associated with delayed or slower age-related cognitive decline. In addition, emerging evidence links sleep dysfunction and dementia, with amyloid deposition being a possible mediator. Summary: Data from further clinical trials are needed before more definitive conclusions can be drawn regarding the efficacy of these lifestyle interventions for lowering the risk of incident dementia and cognitive decline. Nevertheless, it is reasonable to make recommendations to our patients to adopt certain dietary changes and to engage in regular physical activity to improve cardiovascular risk factors for dementia. It is also reasonable to include questions on sleep during cognitive evaluations of the elderly, given the common co-occurrence of sleep dysfunction and cognitive impairment in the elderly population.
AB - Purpose of Review: Diet, physical activity, and sleep are three major modifiable lifestyle factors. This selective review examines the evidence for strong and reliable associations between these three lifestyle factors and risk of dementia and cognitive decline, in an effort to assist clinicians with providing more informed answers to the common questions they face from patients. Recent Findings: Certain aspects of nutrition can decrease risk for dementia. Physical activity has also been associated with delayed or slower age-related cognitive decline. In addition, emerging evidence links sleep dysfunction and dementia, with amyloid deposition being a possible mediator. Summary: Data from further clinical trials are needed before more definitive conclusions can be drawn regarding the efficacy of these lifestyle interventions for lowering the risk of incident dementia and cognitive decline. Nevertheless, it is reasonable to make recommendations to our patients to adopt certain dietary changes and to engage in regular physical activity to improve cardiovascular risk factors for dementia. It is also reasonable to include questions on sleep during cognitive evaluations of the elderly, given the common co-occurrence of sleep dysfunction and cognitive impairment in the elderly population.
UR - http://www.scopus.com/inward/record.url?scp=85056621836&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85056621836&partnerID=8YFLogxK
U2 - 10.1007/s13668-018-0247-9
DO - 10.1007/s13668-018-0247-9
M3 - Review article
C2 - 30413973
AN - SCOPUS:85056621836
SN - 2161-3311
VL - 7
SP - 335
EP - 345
JO - Current Nutrition Reports
JF - Current Nutrition Reports
IS - 4
ER -