Differential inactivation of polymorphic variants of human O⁶-alkylguanine-DNA alkyltransferase

Keyphrases

• Clinical Trials 100%
• O6-methylguanine-DNA Methyltransferase 100%
• Polymorphic Variants 100%
• Hydroxymethyl 33%
• Resistance Sources 33%
• Esters 33%
• Benzyl 33%
• Acid Esters 33%
• Rare Variants 33%
• Folic Acid 33%
• Alkylating Agents 33%
• DNA Repair Enzymes 33%
• O6-methylguanine 33%
• Folate 33%
• Human DNA 33%
• 2′-Deoxyguanosine 33%
• Human Polymorphism 33%
• Folate Derivatives 33%
• Benzylguanine 33%
• MGMT Gene 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Clinical Trial 100%
• 6 O Alkylguanine DNA Alkyltransferase 100%
• Folic Acid 66%
• Alkylating Agent 33%
• Deoxyguanosine 33%
• 6 O Benzylguanine 33%