Differential metabolic consequences of fumarate hydratase and respiratory chain defects

Keyphrases

• Metabolic Consequences 100%
• Respiratory Chain Deficiency 100%
• Fumarate Hydratase 100%
• Tumorigenesis 30%
• Fumarate 30%
• Lactic Acidosis 20%
• Stroke Mimics 20%
• Fumarate Hydratase Deficiency 20%
• Glutathione Level 10%
• Oxidative Stress 10%
• Neuropathy 10%
• Mitochondrial DNA mutation 10%
• Disability 10%
• Energy Metabolism 10%
• Ataxia 10%
• Mutant Lines 10%
• Hypoxia Response 10%
• Unknown Function 10%
• Tricarboxylic Acid Cycle (TCA cycle) 10%
• Cancer Types 10%
• Hypoxia-inducible factor-1α (HIF-1α) 10%
• Redox State 10%
• Glycolysis 10%
• Tumor Formation 10%
• Human Fibroblasts 10%
• Production Pathway 10%
• Leiomyoma 10%
• Disease Phenotype 10%
• Redox Environment 10%
• Encephalopathy 10%
• Premature Death 10%
• Tissue-specific Response 10%
• Retinitis pigmentosa 10%
• Progressive Neurological Disease 10%
• ATP Production 10%
• Primary Fibroblasts 10%

Biochemistry, Genetics and Molecular Biology

• MELAS Syndrome 50%
• Neuropathy, Ataxia, and Retinitis Pigmentosa 25%

Medicine and Dentistry

• MELAS Syndrome 16%
• NARP Syndrome 8%
• Encephalomyopathy 8%