Diffusion-controlled polymer dissolution and drug release

J. S. Vrentas, C. M. Vrentas

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


A model is formulated for diffusion-controlled polymer dissolution and simultaneous drug release for amorphous, uncrosslinked polymers. Calculated fractional drug release versus time curves are similar to experimental curves reported in the literature. Solutions of the transport equations provide a way of illustrating how polymer type and molecular weight can be used in an attempt to approach a constant drug release rate.

Original languageEnglish (US)
Pages (from-to)92-99
Number of pages8
JournalJournal of Applied Polymer Science
Issue number1
StatePublished - Jul 5 2004

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Surfaces, Coatings and Films
  • Polymers and Plastics
  • Materials Chemistry


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