DNA-binding mechanism of O⁶-alkylguanine-DNA alkyltransferase: Effects of protein and DNA alkylation on complex stability

Keyphrases

• Alkylation 100%
• DNA Binding 100%
• Protein Alkylation 100%
• Binding Mechanism 100%
• O6-methylguanine-DNA Methyltransferase 100%
• Complex Stability 100%
• Active Site mutant 100%
• DNA Alkylation 100%
• Single-stranded DNA (ssDNA) 50%
• Oligonucleotides 50%
• Tumor 50%
• Duplex DNA 50%
• Electrophoretic Mobility Shift Assay 50%
• Double Strand 50%
• Deoxyribonucleotides 50%
• Alkyl 50%
• DNA Oligonucleotides 50%
• DNA Repair 50%
• Mutagenic Effects 50%
• Alkylating Agents 50%
• Complex Formation 50%
• Cytotoxic Effect 50%
• Short DNA 50%
• Cooperative Interaction 50%
• Analytical Ultracentrifugation 50%
• Complex Stoichiometry 50%

Biochemistry, Genetics and Molecular Biology

• Oligonucleotide 100%
• Active Site 100%
• DNA Binding 100%
• Stoichiometry 50%
• Alkylation 50%
• Electrophoretic Mobility Shift Assay 50%
• DNA Repair 50%
• Complex Formation 50%
• Cytotoxicity 50%
• Ultracentrifugation 50%
• Mutagenic Activity 50%

Pharmacology, Toxicology and Pharmaceutical Science

• 6 O Alkylguanine DNA Alkyltransferase 100%
• Neoplasm 50%
• Monomer 50%
• Single Stranded DNA 50%
• Electrophoretic Mobility Shift Assay 50%
• Double Stranded DNA 50%
• Alkylating Agent 50%
• Deoxyribonucleotide 50%