DNA Damage Discrimination at Stalled Replication Forks by the Rad5 Homologs HLTF and SHPRH

George Lucian Moldovan; Alan D. D'Andrea

doi:10.1016/j.molcel.2011.03.018

DNA Damage Discrimination at Stalled Replication Forks by the Rad5 Homologs HLTF and SHPRH

George Lucian Moldovan, Alan D. D'Andrea

Research output: Contribution to journal › Short survey › peer-review

9 Scopus citations

Abstract

In this issue of Molecular Cell, Lin et al. (2011) describe how HLTF and SHPRH, the human homologs of yeast Rad5, can discriminate between MMS-induced versus UV-induced DNA damage. The results have important implications for the suppression of damage-specific mutagenesis and for the maintenance of genomic stability.

Original language	English (US)
Pages (from-to)	141-143
Number of pages	3
Journal	Molecular cell
Volume	42
Issue number	2
DOIs	https://doi.org/10.1016/j.molcel.2011.03.018
State	Published - Apr 22 2011

All Science Journal Classification (ASJC) codes

Molecular Biology
Cell Biology

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10.1016/j.molcel.2011.03.018

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title = "DNA Damage Discrimination at Stalled Replication Forks by the Rad5 Homologs HLTF and SHPRH",

abstract = "In this issue of Molecular Cell, Lin et al. (2011) describe how HLTF and SHPRH, the human homologs of yeast Rad5, can discriminate between MMS-induced versus UV-induced DNA damage. The results have important implications for the suppression of damage-specific mutagenesis and for the maintenance of genomic stability.",

author = "Moldovan, {George Lucian} and D'Andrea, {Alan D.}",

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T1 - DNA Damage Discrimination at Stalled Replication Forks by the Rad5 Homologs HLTF and SHPRH

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AU - D'Andrea, Alan D.

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N2 - In this issue of Molecular Cell, Lin et al. (2011) describe how HLTF and SHPRH, the human homologs of yeast Rad5, can discriminate between MMS-induced versus UV-induced DNA damage. The results have important implications for the suppression of damage-specific mutagenesis and for the maintenance of genomic stability.

AB - In this issue of Molecular Cell, Lin et al. (2011) describe how HLTF and SHPRH, the human homologs of yeast Rad5, can discriminate between MMS-induced versus UV-induced DNA damage. The results have important implications for the suppression of damage-specific mutagenesis and for the maintenance of genomic stability.

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JO - Molecular cell

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DNA Damage Discrimination at Stalled Replication Forks by the Rad5 Homologs HLTF and SHPRH

Abstract

All Science Journal Classification (ASJC) codes

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