DNA-directed assembly of gold nanowires on complementary surfaces

Jeremiah K.N. Mbindyo, Brian D. Reiss, Benjamin R. Martin, Christine D. Keating, Michael J. Natan, Thomas E. Mallouk

Research output: Contribution to journalArticlepeer-review

301 Scopus citations


Deoxyribonucleic acid (DNA)-derivatized gold nanowires were discussed as the building blocks of surface assemblies. Oligonucleotides were adsorbed as monolayer coatings on the wires through gold-thiol linkages. Absorption and fluorescence spectroscopy were employed to quantify the amount of DNA bound. The nanowires were modified with single stranded (ss) DNA at specific sites with the remaining wire covered by passivating monolayers. The modification resulted in easy implementation of the site-specific DNA directed assembly.

Original languageEnglish (US)
Pages (from-to)249-254
Number of pages6
JournalAdvanced Materials
Issue number4
StatePublished - Feb 19 2001

All Science Journal Classification (ASJC) codes

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering


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