Down-regulation of 14-3-3 isoforms and annexin A5 proteins in lung adenocarcinoma induced by the tobacco-specific nitrosamine NNK in the A/J mouse revealed by proteomic analysis

Keyphrases

• N-nitrosamines 100%
• Lung 100%
• Proteomic Analysis 100%
• Lung Adenocarcinoma 100%
• Annexin A5 100%
• 14-3-3 Isoforms 100%
• Early Detection 33%
• Carcinogen 33%
• Mass Spectrometry 33%
• Immunoblotting 33%
• Differentially Expressed 33%
• Control Method 33%
• Chemoprevention Trial 33%
• Myosin 33%
• Protein Level 33%
• Mouse Model 33%
• Methylene 33%
• 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 33%
• Protein Isoforms 33%
• Polypeptide 33%
• Vehicle Control 33%
• Two-dimensional Difference Gel Electrophoresis 33%
• Proteasome Subunits 33%
• Chemopreventive 33%
• Biological Function 33%
• Tubulin 33%
• Clara Cell 33%
• Mouse Lung 33%
• Selenocyanate 33%
• Vimentin 33%
• 14-3-3 Protein 33%
• Lung Carcinogenesis 33%
• Antitrypsin 33%
• Dihydropyrimidinase 33%
• GDP Dissociation Inhibitor 33%
• Sec14 33%
• Lung Clinical 33%
• CC10 33%
• Surrogate Tissue 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Tobacco-Specific Nitrosamines 100%
• Nicotine-Derived Nitrosamine Ketone 100%
• Lung Adenocarcinoma 100%
• A J Mouse 100%
• Lipocortin 5 100%
• Mouse 60%
• Carcinogen 20%
• Chemopreventive Agents 20%
• Synapsin I 20%
• Carbene 20%
• 4 (Methylnitrosamino) 1 (3 Pyridyl) 1 Butanone 20%
• Mouse Model 20%
• Polypeptide 20%
• Tubulin 20%
• Western Blot 20%
• Proteasome 20%
• Vimentin 20%
• Difference Gel Electrophoresis 20%
• Isoprotein 20%
• Lung Carcinogenesis 20%
• Trypsin Inhibitor 20%
• Dihydropyrimidinase 20%
• Rho Guanine Nucleotide Dissociation Inhibitor 20%
• Protein 14 3 3 20%