Dragmacidin e synthesis studies. Preparation of a model heptacyclic core structure

Ken S. Feldman, Paiboon Ngernmeesri

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

The conversion of a cycloheptannelated indole platform into the heptacyclic core structure of dragmacidin E proceeded over nine steps. Key sequences include a cyclocondensation to form an intermediate dihydropyrazinone ring and the conversion of a cyclic urea into the cyclic guanidine of the target.

Original languageEnglish (US)
Pages (from-to)4502-4505
Number of pages4
JournalOrganic Letters
Volume12
Issue number20
DOIs
StatePublished - Oct 15 2010

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint

Dive into the research topics of 'Dragmacidin e synthesis studies. Preparation of a model heptacyclic core structure'. Together they form a unique fingerprint.

Cite this