Abstract
The conversion of a cycloheptannelated indole platform into the heptacyclic core structure of dragmacidin E proceeded over nine steps. Key sequences include a cyclocondensation to form an intermediate dihydropyrazinone ring and the conversion of a cyclic urea into the cyclic guanidine of the target.
Original language | English (US) |
---|---|
Pages (from-to) | 4502-4505 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 12 |
Issue number | 20 |
DOIs | |
State | Published - Oct 15 2010 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry