Abstract
The conversion of a cycloheptannelated indole platform into the heptacyclic core structure of dragmacidin E proceeded over nine steps. Key sequences include a cyclocondensation to form an intermediate dihydropyrazinone ring and the conversion of a cyclic urea into the cyclic guanidine of the target.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4502-4505 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 12 |
| Issue number | 20 |
| DOIs | |
| State | Published - Oct 15 2010 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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