TY - JOUR
T1 - Drug delivery behavior of titania nanotube arrays coated with chitosan polymer
AU - Shidfar, Shahrzad
AU - Tavangarian, Fariborz
AU - Nemati, Nahid Hassanzadeh
AU - Fahami, Abbas
N1 - Publisher Copyright:
© 2017 Elsevier Ltd
PY - 2017/6
Y1 - 2017/6
N2 - Titania nanotube (TNT) arrays with the length to diameter ratio of 85:1 were synthetized after anodizing the specimens at the anodizing voltage of 55 V for 2 h. Ultrasonic cleaning procedure in deionized water caused the formation of micro-cracks, clusters of TNT bundles and distortion of the nanotubes; however, acetone medium decreased the risk of fracture and the formation of clusters. To control the drug delivery rate, chitosan polymer was deposited on the surface of TNTs using dip-coating process. The total release of TNTs with 0, 0.29 and 0.45 μm chitosan coating thickness was about 6, 8 and 12 days, respectively.
AB - Titania nanotube (TNT) arrays with the length to diameter ratio of 85:1 were synthetized after anodizing the specimens at the anodizing voltage of 55 V for 2 h. Ultrasonic cleaning procedure in deionized water caused the formation of micro-cracks, clusters of TNT bundles and distortion of the nanotubes; however, acetone medium decreased the risk of fracture and the formation of clusters. To control the drug delivery rate, chitosan polymer was deposited on the surface of TNTs using dip-coating process. The total release of TNTs with 0, 0.29 and 0.45 μm chitosan coating thickness was about 6, 8 and 12 days, respectively.
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U2 - 10.1016/j.md.2017.09.002
DO - 10.1016/j.md.2017.09.002
M3 - Article
AN - SCOPUS:85029838475
SN - 2352-9245
VL - 8
SP - 9
EP - 17
JO - Materials Discovery
JF - Materials Discovery
ER -