Abstract
This study reports a nanobiosensor for dynamic single-cell gene analysis during collective cancer invasion in 3D microenvironments. By incorporating multiphoton microscopy and a 3D cancer invasion assay, we perform dynamic gene expression during cancer invasion and characterize invasive leader cells in 3D microenvironments. Our results underscores the significance of the Notch signaling in the regulation of invasive leader cells during 3D collective cancer invasion.
| Original language | English (US) |
|---|---|
| Title of host publication | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 459-460 |
| Number of pages | 2 |
| ISBN (Electronic) | 9780979806490 |
| State | Published - 2016 |
| Event | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland Duration: Oct 9 2016 → Oct 13 2016 |
Publication series
| Name | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|
Other
| Other | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|---|
| Country/Territory | Ireland |
| City | Dublin |
| Period | 10/9/16 → 10/13/16 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
All Science Journal Classification (ASJC) codes
- Control and Systems Engineering
Fingerprint
Dive into the research topics of 'Dynamic characterization of invasive leader cells during 3D collective cancer invasion'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver