Dynamics of nucleosome assembly and effects of DNA methylation

Ju Yeon Lee; Jaehyoun Lee; Hongjun Yue; Tae Hee Lee

doi:10.1074/jbc.M114.619213

Dynamics of nucleosome assembly and effects of DNA methylation

Ju Yeon Lee, Jaehyoun Lee, Hongjun Yue, Tae Hee Lee

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Abstract

Background: Nucleosome assembly mediated by histone chaperones and DNA methylation play important roles in gene regulation. Results: Dynamics of nucleosome assembly with and without CpG methylation was investigated. Conclusion: CpG methylation increases the efficiency of nucleosome assembly. Significance: CpG methylation accelerates nucleosome formation that may facilitate gene packaging in chromatin.

Original language	English (US)
Pages (from-to)	4291-4303
Number of pages	13
Journal	Journal of Biological Chemistry
Volume	290
Issue number	7
DOIs	https://doi.org/10.1074/jbc.M114.619213
State	Published - Feb 13 2015

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Cell Biology

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10.1074/jbc.M114.619213

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title = "Dynamics of nucleosome assembly and effects of DNA methylation",

abstract = "Background: Nucleosome assembly mediated by histone chaperones and DNA methylation play important roles in gene regulation. Results: Dynamics of nucleosome assembly with and without CpG methylation was investigated. Conclusion: CpG methylation increases the efficiency of nucleosome assembly. Significance: CpG methylation accelerates nucleosome formation that may facilitate gene packaging in chromatin.",

author = "Lee, {Ju Yeon} and Jaehyoun Lee and Hongjun Yue and Lee, {Tae Hee}",

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AU - Yue, Hongjun

AU - Lee, Tae Hee

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Y1 - 2015/2/13

N2 - Background: Nucleosome assembly mediated by histone chaperones and DNA methylation play important roles in gene regulation. Results: Dynamics of nucleosome assembly with and without CpG methylation was investigated. Conclusion: CpG methylation increases the efficiency of nucleosome assembly. Significance: CpG methylation accelerates nucleosome formation that may facilitate gene packaging in chromatin.

AB - Background: Nucleosome assembly mediated by histone chaperones and DNA methylation play important roles in gene regulation. Results: Dynamics of nucleosome assembly with and without CpG methylation was investigated. Conclusion: CpG methylation increases the efficiency of nucleosome assembly. Significance: CpG methylation accelerates nucleosome formation that may facilitate gene packaging in chromatin.

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Dynamics of nucleosome assembly and effects of DNA methylation

Abstract

All Science Journal Classification (ASJC) codes

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