Dynamics of nucleosome assembly and effects of DNA methylation

Ju Yeon Lee; Jaehyoun Lee; Hongjun Yue; Tae Hee Lee

doi:10.1074/jbc.M114.619213

Dynamics of nucleosome assembly and effects of DNA methylation

Ju Yeon Lee, Jaehyoun Lee, Hongjun Yue, Tae Hee Lee

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Background: Nucleosome assembly mediated by histone chaperones and DNA methylation play important roles in gene regulation. Results: Dynamics of nucleosome assembly with and without CpG methylation was investigated. Conclusion: CpG methylation increases the efficiency of nucleosome assembly. Significance: CpG methylation accelerates nucleosome formation that may facilitate gene packaging in chromatin.

Original language	English (US)
Pages (from-to)	4291-4303
Number of pages	13
Journal	Journal of Biological Chemistry
Volume	290
Issue number	7
DOIs	https://doi.org/10.1074/jbc.M114.619213
State	Published - Feb 13 2015

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Cell Biology

Access to Document

10.1074/jbc.M114.619213

Cite this

@article{0a7ecb3ddb334c1d9a17ef3910fd8d64,

title = "Dynamics of nucleosome assembly and effects of DNA methylation",

abstract = "Background: Nucleosome assembly mediated by histone chaperones and DNA methylation play important roles in gene regulation. Results: Dynamics of nucleosome assembly with and without CpG methylation was investigated. Conclusion: CpG methylation increases the efficiency of nucleosome assembly. Significance: CpG methylation accelerates nucleosome formation that may facilitate gene packaging in chromatin.",

author = "Lee, {Ju Yeon} and Jaehyoun Lee and Hongjun Yue and Lee, {Tae Hee}",

note = "Publisher Copyright: {\textcopyright} 2015 by The American Society for Biochemistry and Molecular Biology, Inc. Published in the U.S.A.",

year = "2015",

month = feb,

day = "13",

doi = "10.1074/jbc.M114.619213",

language = "English (US)",

volume = "290",

pages = "4291--4303",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology Inc.",

number = "7",

}

TY - JOUR

T1 - Dynamics of nucleosome assembly and effects of DNA methylation

AU - Lee, Ju Yeon

AU - Lee, Jaehyoun

AU - Yue, Hongjun

AU - Lee, Tae Hee

PY - 2015/2/13

Y1 - 2015/2/13

N2 - Background: Nucleosome assembly mediated by histone chaperones and DNA methylation play important roles in gene regulation. Results: Dynamics of nucleosome assembly with and without CpG methylation was investigated. Conclusion: CpG methylation increases the efficiency of nucleosome assembly. Significance: CpG methylation accelerates nucleosome formation that may facilitate gene packaging in chromatin.

AB - Background: Nucleosome assembly mediated by histone chaperones and DNA methylation play important roles in gene regulation. Results: Dynamics of nucleosome assembly with and without CpG methylation was investigated. Conclusion: CpG methylation increases the efficiency of nucleosome assembly. Significance: CpG methylation accelerates nucleosome formation that may facilitate gene packaging in chromatin.

UR - http://www.scopus.com/inward/record.url?scp=84922762920&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84922762920&partnerID=8YFLogxK

U2 - 10.1074/jbc.M114.619213

DO - 10.1074/jbc.M114.619213

M3 - Article

C2 - 25550164

AN - SCOPUS:84922762920

SN - 0021-9258

VL - 290

SP - 4291

EP - 4303

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 7

ER -

Dynamics of nucleosome assembly and effects of DNA methylation

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this