Dynamics of Telomere Rejuvenation during Chemical Induction to Pluripotent Stem Cells

Haifeng Fu, Cheng lei Tian, Xiaoying Ye, Xiaoyan Sheng, Hua Wang, Yifei Liu, Lin Liu

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

In this article, Liu and colleagues show that telomere rejuvenation links to reprogramming and pluripotency of CiPSCs. Moreover, crotonylation induced by crotonic acid facilitates telomere maintenance and enhances chemically induced reprogramming to pluripotency.

Original languageEnglish (US)
Pages (from-to)70-87
Number of pages18
JournalStem Cell Reports
Volume11
Issue number1
DOIs
StatePublished - Jul 10 2018

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Genetics
  • Developmental Biology
  • Cell Biology

Cite this