EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

Luca Giovanella, Anca M. Avram, Ioannis Iakovou, Jennifer Kwak, Susan A. Lawson, Elizabeth Lulaj, Markus Luster, Arnoldo Piccardo, Matthias Schmidt, Mark Tulchinsky, Frederick A. Verburg, Ely Wolin

Research output: Contribution to journalArticlepeer-review

95 Scopus citations


Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the 99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.

Original languageEnglish (US)
Pages (from-to)2514-2525
Number of pages12
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Issue number12
StatePublished - Nov 1 2019

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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