EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

Luca Giovanella; Anca M. Avram; Ioannis Iakovou; Jennifer Kwak; Susan A. Lawson; Elizabeth Lulaj; Markus Luster; Arnoldo Piccardo; Matthias Schmidt; Mark Tulchinsky; Frederick A. Verburg; Ely Wolin

doi:10.1007/s00259-019-04472-8

EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

Luca Giovanella, Anca M. Avram, Ioannis Iakovou, Jennifer Kwak, Susan A. Lawson, Elizabeth Lulaj, Markus Luster, Arnoldo Piccardo, Matthias Schmidt, Mark Tulchinsky, Frederick A. Verburg, Ely Wolin

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117 Scopus citations

Abstract

Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the ^99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.

Original language	English (US)
Pages (from-to)	2514-2525
Number of pages	12
Journal	European Journal of Nuclear Medicine and Molecular Imaging
Volume	46
Issue number	12
DOIs	https://doi.org/10.1007/s00259-019-04472-8
State	Published - Nov 1 2019

All Science Journal Classification (ASJC) codes

Radiology Nuclear Medicine and imaging

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Giovanella, L., Avram, A. M., Iakovou, I., Kwak, J., Lawson, S. A., Lulaj, E., Luster, M., Piccardo, A., Schmidt, M., Tulchinsky, M., Verburg, F. A., & Wolin, E. (2019). EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy. European Journal of Nuclear Medicine and Molecular Imaging, 46(12), 2514-2525. https://doi.org/10.1007/s00259-019-04472-8

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abstract = "Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the 99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.",

author = "Luca Giovanella and Avram, {Anca M.} and Ioannis Iakovou and Jennifer Kwak and Lawson, {Susan A.} and Elizabeth Lulaj and Markus Luster and Arnoldo Piccardo and Matthias Schmidt and Mark Tulchinsky and Verburg, {Frederick A.} and Ely Wolin",

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AU - Avram, Anca M.

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AU - Kwak, Jennifer

AU - Lawson, Susan A.

AU - Lulaj, Elizabeth

AU - Luster, Markus

AU - Piccardo, Arnoldo

AU - Schmidt, Matthias

AU - Tulchinsky, Mark

AU - Verburg, Frederick A.

AU - Wolin, Ely

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N2 - Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the 99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.

AB - Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the 99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.

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EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

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