Early Detection and Staging of Lung Fibrosis Enabled by Collagen-Targeted MRI Protein Contrast Agent

Keyphrases

• Early Detection 100%
• Collagen 100%
• Lung Fibrosis 100%
• Idiopathic Pulmonary Fibrosis 66%
• Chronic Obstructive Pulmonary Disease 50%
• Lung Disease 33%
• Mouse Model 33%
• Chronic Lung Disease 33%
• Excellent Sensitivity 16%
• Signal-to-noise Ratio 16%
• Metal Affinity 16%
• Effective Treatment 16%
• Fibrosis 16%
• Histological Analysis 16%
• Drug Treatment 16%
• Early Diagnosis 16%
• Gd3+ 16%
• Robust Detection 16%
• Cause of Death 16%
• Poor Prognosis 16%
• Spatially Heterogeneous 16%
• Collagen Deposition 16%
• Diagnosis Treatment 16%
• Type I Collagen 16%
• Contrast Agent 16%
• Treatment Monitoring 16%
• Histopathological Correlation 16%
• Heterogeneous Distribution 16%
• Bleomycin 16%
• Lung Parenchyma 16%
• MRI Contrast Agent 16%
• Binding Selectivity 16%
• Translational Potential 16%
• Pulmonary Fibrosis 16%
• MRI Signal 16%
• Non-invasive Detection 16%
• Lung Airways 16%
• Stage-dependent 16%
• Collagen I 16%
• MR Imaging Technique 16%
• Exertional Dyspnea 16%
• Lung Cancer Progression 16%
• Transmetalation 16%
• R1 Relaxivity 16%
• Heterogeneous Mapping 16%
• Targeted Protein 16%
• Traction Bronchiectasis 16%

Medicine and Dentistry

• Magnetic Resonance Imaging 100%
• Idiopathic Pulmonary Fibrosis 100%
• Contrast Medium 100%
• Pulmonary Fibrosis 100%
• Chronic Obstructive Pulmonary Disease 75%
• Silo-Filler's Disease 50%
• Chronic Lung Disease 50%
• Drug Therapy 25%
• Fibrosis 25%
• Binding Affinity 25%
• Sensitivity and Specificity 25%
• Collagen Type 1 25%
• Early Diagnosis 25%
• Patient Monitoring 25%
• Disease Exacerbation 25%
• Imaging Technique 25%
• Dyspnea 25%
• Metal Binding 25%
• Bleomycin 25%
• Lung Parenchyma 25%
• Electronic Cigarette 25%
• Signal-to-Noise Ratio 25%
• MRI Contrast Agent 25%
• Lung 25%
• Bronchiectasis 25%
• Effective Treatment 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Fibrosing Alveolitis 100%
• Contrast Medium 100%
• Lung Fibrosis 100%
• Chronic Obstructive Lung Disease 75%
• Mouse Model 50%
• Lung Disease 50%
• Chronic Lung Disease 50%
• Disease Exacerbation 25%
• Collagen Type 1 25%
• Fibrosis 25%
• Pharmacotherapy 25%
• Dyspnea 25%
• Interstitial Pneumonia 25%
• Bleomycin 25%
• Electronic Cigarette 25%
• Bronchiectasis 25%