TY - JOUR
T1 - Early detection in lung cancer
T2 - Case finding and screening
AU - Wolpaw, Daniel
PY - 1996
Y1 - 1996
N2 - Lung cancer, a common and deadly disease, is a tempting target for programs of intervention based on early detection. These programs have been hampered by the biologic variability of the disease and by imperfect detection tools (chest radiography and sputum cytology). Multiple large clinical studies over the past 40 years have failed to demonstrate a favorable impact of screening on the mortality rate from lung cancer. Medical decision making in this area must be baked on an understanding of the pros and cons of early detection and an appreciation of the difference between screening and individualized case finding.
AB - Lung cancer, a common and deadly disease, is a tempting target for programs of intervention based on early detection. These programs have been hampered by the biologic variability of the disease and by imperfect detection tools (chest radiography and sputum cytology). Multiple large clinical studies over the past 40 years have failed to demonstrate a favorable impact of screening on the mortality rate from lung cancer. Medical decision making in this area must be baked on an understanding of the pros and cons of early detection and an appreciation of the difference between screening and individualized case finding.
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U2 - 10.1016/S0025-7125(05)70427-2
DO - 10.1016/S0025-7125(05)70427-2
M3 - Article
C2 - 8569301
AN - SCOPUS:0030029449
SN - 0025-7125
VL - 80
SP - 63
EP - 82
JO - Medical Clinics of North America
JF - Medical Clinics of North America
IS - 1
ER -
