TY - JOUR
T1 - Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma
AU - Chamberlain, Marc C.
AU - Glantz, Michael
AU - Chalmers, Lisa
AU - Van Horn, Alixis
AU - Sloan, Andrew E.
PY - 2007/3/1
Y1 - 2007/3/1
N2 - Concurrent temozolomide (TMZ) and radiotherapy is the new standard of care for patients with newly diagnosed glioblastoma. In 51 consecutive patients treated according to this regimen, 7 patients (14%) manifested surgically confirmed early necrosis without evidence of recurrent tumor. This observation suggests that daily TMZ may represent a potent radiosensitizing regimen.
AB - Concurrent temozolomide (TMZ) and radiotherapy is the new standard of care for patients with newly diagnosed glioblastoma. In 51 consecutive patients treated according to this regimen, 7 patients (14%) manifested surgically confirmed early necrosis without evidence of recurrent tumor. This observation suggests that daily TMZ may represent a potent radiosensitizing regimen.
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U2 - 10.1007/s11060-006-9241-y
DO - 10.1007/s11060-006-9241-y
M3 - Article
C2 - 16944309
AN - SCOPUS:33846955124
SN - 0167-594X
VL - 82
SP - 81
EP - 83
JO - Journal of neuro-oncology
JF - Journal of neuro-oncology
IS - 1
ER -