TY - JOUR
T1 - Early puberty in girls
T2 - The case of premature adrenarche
AU - Dorn, Lorah D.
AU - Rotenstein, Deborah
N1 - Funding Information:
Components of this article were presented by the first author in an invited address to the Society for Menstrual Cycle Research, June 2003 in Pittsburgh, Pennsylvania. Support was received by the first author from a grant from the National Institute of Mental Health (R01 MH59892-01A3). Deborah Rotenstein, MD, is a pediatric endocrinologist with interests in early puberty, precocious adrenarche, PCOS and Adrenal hyperplasia. Her research interests also extend to growth and pubertal issues for patients with myelomeningocele.
PY - 2004/11
Y1 - 2004/11
N2 - In this article we examine the issue of early puberty in girls. First, a brief overview of normal pubertal development is provided, including the two endocrine components of puberty: gonadarche and adrenarche. Second, we critically discuss the controversy regarding whether puberty truly is occurring earlier in girls. Third, we emphasize one type of early puberty, the case of premature adrenarche (PA). PA is used to illustrate the importance of identifying types of early puberty, evaluating the types to determine causality, determining whether follow-up of early puberty is necessary, and showing the potential ramifications of ignoring this variation in pubertal development. Findings from a pilot study comparing PA and on-time puberty children are used to show the importance of determining whether early puberty is normal in all cases.
AB - In this article we examine the issue of early puberty in girls. First, a brief overview of normal pubertal development is provided, including the two endocrine components of puberty: gonadarche and adrenarche. Second, we critically discuss the controversy regarding whether puberty truly is occurring earlier in girls. Third, we emphasize one type of early puberty, the case of premature adrenarche (PA). PA is used to illustrate the importance of identifying types of early puberty, evaluating the types to determine causality, determining whether follow-up of early puberty is necessary, and showing the potential ramifications of ignoring this variation in pubertal development. Findings from a pilot study comparing PA and on-time puberty children are used to show the importance of determining whether early puberty is normal in all cases.
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U2 - 10.1016/j.whi.2004.08.008
DO - 10.1016/j.whi.2004.08.008
M3 - Article
C2 - 15589767
AN - SCOPUS:10044256606
SN - 1049-3867
VL - 14
SP - 177
EP - 183
JO - Women's Health Issues
JF - Women's Health Issues
IS - 6
ER -
