Effect of drug dose and timing of treatment on the emergence of drug resistance in vivo in a malaria model

Keyphrases

• Drug Effects 100%
• Drug Dosing 100%
• Drug Resistance 100%
• Malaria Model 100%
• Resistance Emergence 100%
• Treatment Timing 100%
• Time-to-treatment 60%
• Atovaquone 60%
• High Dose 40%
• Drug Treatment 40%
• High-level Resistance 40%
• Malaria 20%
• Treatment Regimen 20%
• Mouse Model 20%
• Biological Context 20%
• Laboratory Mice 20%
• Antimalarial Drugs 20%
• Late Treatment 20%
• Pathogen Population 20%
• Resistant mutants 20%
• Inoculum 20%
• Plasmodium Chabaudi 20%
• Post-infection 20%
• Right Time 20%
• Effective Compounds 20%
• Inoculum Size 20%
• Drug Treatment Regimen 20%
• Large Population Size 20%
• Dose Timing 20%
• Lay Summary 20%
• Resistance Evolution 20%
• Drug Resistance Evolution 20%

Immunology and Microbiology

• Drug Resistance 100%
• Drug Dose 100%
• Atovaquone 100%
• Drug Therapy 100%
• Drug Megadose 66%
• Inoculum 66%
• Infectious Agent 33%
• Mouse Model 33%
• Antimalarial Agent 33%
• Population Size 33%
• Plasmodium chabaudi 33%
• Experimental Mouse 33%
• Antimicrobial Resistance 33%