Abstract
Inverse-electron demand Diels-Alder reactions of 1,3,5-triazines and 2-aminopyrroles are facilitated by electron-withdrawing groups (EWG) on both reactants. Whereas HOMO-LUMO calculations predict that EWG on 2-aminopyrroles should lower the relative rate of reaction. This apparent contradiction can be explained if the reaction cascade is under equilibrium control with at least one reversible step.
Original language | English (US) |
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Pages (from-to) | 97-100 |
Number of pages | 4 |
Journal | Heterocyclic Communications |
Volume | 13 |
Issue number | 2-3 |
DOIs | |
State | Published - 2007 |
All Science Journal Classification (ASJC) codes
- Organic Chemistry