Effect of Enzogenol® Supplementation on Cognitive, Executive, and Vestibular/Balance Functioning in Chronic Phase of Concussion

A. Walter; K. Finelli; X. Bai; P. Arnett; T. Bream; P. Seidenberg; S. Lynch; B. Johnson; S. Slobounov

doi:10.1080/87565641.2016.1256404

Effect of Enzogenol® Supplementation on Cognitive, Executive, and Vestibular/Balance Functioning in Chronic Phase of Concussion

A. Walter, K. Finelli, X. Bai, P. Arnett, T. Bream, P. Seidenberg, S. Lynch, B. Johnson, S. Slobounov

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

This study examined the feasibility of Enzogenol® as a potential treatment modality for concussed individuals with residual symptoms in the chronic phase. Forty-two student-athletes with history of sport-related concussion were enrolled, comparing Enzogenol® versus placebo. Testing was conducted using virtual reality (VR) and electroencephalography (EEG), with neuropsychological (NP) tasks primarily used to induce cognitive challenges. After six weeks, the Enzogenol® group showed enhanced frontal-midline theta, and decreased parietal theta power, indicating reduced mental fatigue. Subjects enrolled in the Enzogenol® group also self-reported reduced mental fatigue and sleep problems. This suggests that Enzogenol® has the potential to improve brain functioning in the chronic phase of concussion.

Original language	English (US)
Pages (from-to)	93-103
Number of pages	11
Journal	Developmental Neuropsychology
Volume	42
Issue number	2
DOIs	https://doi.org/10.1080/87565641.2016.1256404
State	Published - Feb 17 2017

All Science Journal Classification (ASJC) codes

Neuropsychology and Physiological Psychology
Developmental and Educational Psychology

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10.1080/87565641.2016.1256404

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abstract = "This study examined the feasibility of Enzogenol{\textregistered} as a potential treatment modality for concussed individuals with residual symptoms in the chronic phase. Forty-two student-athletes with history of sport-related concussion were enrolled, comparing Enzogenol{\textregistered} versus placebo. Testing was conducted using virtual reality (VR) and electroencephalography (EEG), with neuropsychological (NP) tasks primarily used to induce cognitive challenges. After six weeks, the Enzogenol{\textregistered} group showed enhanced frontal-midline theta, and decreased parietal theta power, indicating reduced mental fatigue. Subjects enrolled in the Enzogenol{\textregistered} group also self-reported reduced mental fatigue and sleep problems. This suggests that Enzogenol{\textregistered} has the potential to improve brain functioning in the chronic phase of concussion.",

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AU - Finelli, K.

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AU - Arnett, P.

AU - Bream, T.

AU - Seidenberg, P.

AU - Lynch, S.

AU - Johnson, B.

AU - Slobounov, S.

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Effect of Enzogenol® Supplementation on Cognitive, Executive, and Vestibular/Balance Functioning in Chronic Phase of Concussion

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