Effect of prolonged exercise on plasma prostaglandin levels

Laurence M. Demers, Timothy S. Harrison, David R. Halbert, Richard J. Santen

Research output: Contribution to journalArticlepeer-review

105 Scopus citations


The effects of a strenuous marathon run of 42.2 kilometers on the presence of prostaglandins in blood was investigated in 24 healthy males and females. Testosterone, FSH, LH, epinephrine, norepinephrine, dopamine, T4 and T3 were also measured. With the exercise of the marathon run, a significant elevation of plasma PGE2, PGF2α and 6 keto PGFla was observed in the runners following the race. Significant increases were also noted in blood catecholamine, dopamine and testosterone levels while a significant decline in the gonadotropins, FSH and LH was observed. No changes in thyroxine or tri-iodothyronine were noted.

Original languageEnglish (US)
Pages (from-to)413-418
Number of pages6
JournalProstaglandines and Medicine
Issue number4
StatePublished - Apr 1981

All Science Journal Classification (ASJC) codes

  • General Medicine


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