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Effect of Single Amino Acid Replacements on the Folding and Stability of Dihydrofolate Reductase from Escherichia coli

  • Kathleen M. Perry
  • , C. Robert Matthews
  • , James J. Onuffer
  • , Mitchell S. Gittelman
  • , Jin Tan Chen
  • , Kazunari Taira
  • , Stephen J. Benkovic
  • , Nancy A. Touchette
  • , Cinda S. Herndon
  • , Ruth J. Mayer
  • , Elizabeth E. Howell
  • , Joseph Kraut

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Biochemistry, Genetics and Molecular Biology