Effects of hemodynamic overload on canine myocardial myosin.

J. Wikman-Coffelt; J. McPherson; C. Fenner; M. Lotysh; R. Zelis; D. T. Mason

Effects of hemodynamic overload on canine myocardial myosin.

J. Wikman-Coffelt, J. McPherson, C. Fenner, M. Lotysh, R. Zelis, D. T. Mason

Department of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

After mild banding of pulmonary artery in dogs there was a rapid elevation in protein and RNA synthesis, followed by an elevation in myosin content and myosin ATPase activity. There was an increase in myosin ATPase activity when K+ or Ca++ was used as activator effector but not with the cations, Mn++ or NH4+. Concomitant with an increase in myosin ATPase activity there was a decrease in one of the C1 light chain components, previously named C1d.

Original language	English (US)
Pages (from-to)	253-261
Number of pages	9
Journal	Recent advances in studies on cardiac structure and metabolism
Volume	5
State	Published - 1975

All Science Journal Classification (ASJC) codes

Medicine(all)

Cite this

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title = "Effects of hemodynamic overload on canine myocardial myosin.",

abstract = "After mild banding of pulmonary artery in dogs there was a rapid elevation in protein and RNA synthesis, followed by an elevation in myosin content and myosin ATPase activity. There was an increase in myosin ATPase activity when K+ or Ca++ was used as activator effector but not with the cations, Mn++ or NH4+. Concomitant with an increase in myosin ATPase activity there was a decrease in one of the C1 light chain components, previously named C1d.",

author = "J. Wikman-Coffelt and J. McPherson and C. Fenner and M. Lotysh and R. Zelis and Mason, {D. T.}",

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AU - Wikman-Coffelt, J.

AU - McPherson, J.

AU - Fenner, C.

AU - Lotysh, M.

AU - Zelis, R.

AU - Mason, D. T.

PY - 1975

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N2 - After mild banding of pulmonary artery in dogs there was a rapid elevation in protein and RNA synthesis, followed by an elevation in myosin content and myosin ATPase activity. There was an increase in myosin ATPase activity when K+ or Ca++ was used as activator effector but not with the cations, Mn++ or NH4+. Concomitant with an increase in myosin ATPase activity there was a decrease in one of the C1 light chain components, previously named C1d.

AB - After mild banding of pulmonary artery in dogs there was a rapid elevation in protein and RNA synthesis, followed by an elevation in myosin content and myosin ATPase activity. There was an increase in myosin ATPase activity when K+ or Ca++ was used as activator effector but not with the cations, Mn++ or NH4+. Concomitant with an increase in myosin ATPase activity there was a decrease in one of the C1 light chain components, previously named C1d.

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ER -

Effects of hemodynamic overload on canine myocardial myosin.

Abstract

All Science Journal Classification (ASJC) codes

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