TY - JOUR
T1 - Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy
T2 - A pilot randomized double-blind study
AU - Ladson, Gwinnett
AU - Dodson, William
AU - Sweet, Stephanie D.
AU - Archibong, Anthony E.
AU - Kunselman, Allen
AU - Demers, Laurence
AU - Lee, Peter
AU - Williams, Nancy
AU - Coney, Ponjola
AU - Legro, Richard
N1 - Funding Information:
Supported by PHS U54 HD044315 The Meharry Medical College/Penn State Cooperative Reproductive Science Center and a GCRC grant MO1 RR 10732 , and GCRC construction grant C06 RR016499 to Pennsylvania State University.
PY - 2011/6/30
Y1 - 2011/6/30
N2 - Our small study does not support the addition of metformin to the lifestyle of adolescents. Although there are favorable trends toward hyperandrogenism with metformin, these must be balanced against the increased rate of gastrointestinal side effects. However, other treatments were associated with an improved quality of life.
AB - Our small study does not support the addition of metformin to the lifestyle of adolescents. Although there are favorable trends toward hyperandrogenism with metformin, these must be balanced against the increased rate of gastrointestinal side effects. However, other treatments were associated with an improved quality of life.
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U2 - 10.1016/j.fertnstert.2011.05.048
DO - 10.1016/j.fertnstert.2011.05.048
M3 - Article
C2 - 21704212
AN - SCOPUS:79959687822
SN - 0015-0282
VL - 95
SP - 2595-2598.e6
JO - Fertility and sterility
JF - Fertility and sterility
IS - 8
ER -