TY - GEN
T1 - Effects of synaptic coupling on phase response curve of neurons
AU - Lu, Meili
AU - Che, Yanqiu
AU - Li, Huiyan
AU - Wei, Xile
AU - Wang, Jiang
N1 - Publisher Copyright:
© 2014 IEEE.
PY - 2014
Y1 - 2014
N2 - The problem of phase response curves (PRCs) for two neuronal oscillators coupled with chemical synapse is considered in this paper. For small inputs, the PRCs can be computed for a linearized model for the system on the limit cycle. But for an input with large amplitude, the PRCs could be computed by direct method. The shape of phase response curve for single oscillator is depending on the influence of external stimuli, while in neuron networks, neurons are coupled to each other, and the couplings can affect the response of the neuronal oscillators to stimulation. Based on the direct PRCs, we investigate the effects of excitatory and inhibitory synaptic couplings on the PRCs of oscillators, and find that the effects of couplings on phase response of neurons are not only depending on the nature of couplings, but also on the initial phase errors between coupled neurons, which can be explained by the phase difference coupling function.
AB - The problem of phase response curves (PRCs) for two neuronal oscillators coupled with chemical synapse is considered in this paper. For small inputs, the PRCs can be computed for a linearized model for the system on the limit cycle. But for an input with large amplitude, the PRCs could be computed by direct method. The shape of phase response curve for single oscillator is depending on the influence of external stimuli, while in neuron networks, neurons are coupled to each other, and the couplings can affect the response of the neuronal oscillators to stimulation. Based on the direct PRCs, we investigate the effects of excitatory and inhibitory synaptic couplings on the PRCs of oscillators, and find that the effects of couplings on phase response of neurons are not only depending on the nature of couplings, but also on the initial phase errors between coupled neurons, which can be explained by the phase difference coupling function.
UR - http://www.scopus.com/inward/record.url?scp=84988264029&partnerID=8YFLogxK
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U2 - 10.1109/BMEI.2014.7002872
DO - 10.1109/BMEI.2014.7002872
M3 - Conference contribution
AN - SCOPUS:84988264029
T3 - Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014
SP - 745
EP - 749
BT - Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014
Y2 - 14 October 2014 through 16 October 2014
ER -