Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide

Chen Chen; Biao Yu

doi:10.1016/j.bmcl.2009.03.155

Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide

Chen Chen, Biao Yu

Chemistry

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

An efficient [DEF+GH] route was developed to the synthesis of Idraparinux, which is a fully O-sulfated, O-methylated mimic of the unique Antithrombin III binding domain of heparin.

Original language	English (US)
Pages (from-to)	3875-3879
Number of pages	5
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	19
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2009.03.155
State	Published - Jul 15 2009

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/j.bmcl.2009.03.155

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abstract = "An efficient [DEF+GH] route was developed to the synthesis of Idraparinux, which is a fully O-sulfated, O-methylated mimic of the unique Antithrombin III binding domain of heparin.",

author = "Chen Chen and Biao Yu",

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ER -

Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide

Abstract

All Science Journal Classification (ASJC) codes

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