Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide

Chen Chen; Biao Yu

doi:10.1016/j.bmcl.2009.03.155

Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide

Chen Chen
, Biao Yu

Chemistry

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

An efficient [DEF+GH] route was developed to the synthesis of Idraparinux, which is a fully O-sulfated, O-methylated mimic of the unique Antithrombin III binding domain of heparin.

Original language	English (US)
Pages (from-to)	3875-3879
Number of pages	5
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	19
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2009.03.155
State	Published - Jul 15 2009

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

Access to Document

10.1016/j.bmcl.2009.03.155

Cite this

@article{cde605b7781d49239e614010f7b027cc,

title = "Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide",

abstract = "An efficient [DEF+GH] route was developed to the synthesis of Idraparinux, which is a fully O-sulfated, O-methylated mimic of the unique Antithrombin III binding domain of heparin.",

author = "Chen Chen and Biao Yu",

year = "2009",

month = jul,

day = "15",

doi = "10.1016/j.bmcl.2009.03.155",

language = "English (US)",

volume = "19",

pages = "3875--3879",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Ltd",

number = "14",

}

TY - JOUR

T1 - Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide

AU - Chen, Chen

AU - Yu, Biao

PY - 2009/7/15

Y1 - 2009/7/15

N2 - An efficient [DEF+GH] route was developed to the synthesis of Idraparinux, which is a fully O-sulfated, O-methylated mimic of the unique Antithrombin III binding domain of heparin.

AB - An efficient [DEF+GH] route was developed to the synthesis of Idraparinux, which is a fully O-sulfated, O-methylated mimic of the unique Antithrombin III binding domain of heparin.

UR - https://www.scopus.com/pages/publications/67649819572

UR - https://www.scopus.com/pages/publications/67649819572#tab=citedBy

U2 - 10.1016/j.bmcl.2009.03.155

DO - 10.1016/j.bmcl.2009.03.155

M3 - Article

C2 - 19386495

AN - SCOPUS:67649819572

SN - 0960-894X

VL - 19

SP - 3875

EP - 3879

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 14

ER -

Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this