Eight and a Half Syndrome from Multiple Sclerosis

William K. Jens, Aiesha Ahmed

Research output: Contribution to journalArticlepeer-review


A 50 year old woman with a past medical history of hypertension presented with sudden onset of one-and-a-half syndrome on top of a sub-acute 7th nerve palsy. Her MRI findings showed several contrast enhancing lesions including a pontine lesion. The lumbar puncture (LP) showed oligoclonal bands. Multiple sclerosis (MS) was diagnosed, with the rare initial presentation of eight-and-a-half syndrome. The patient was treated with intravenous steroids, then placed on a disease modifying agent. In this article, we discuss the patient’s imaging and review the pathology of eight-and-a-half syndrome.
Original languageEnglish (US)
JournalJournal of Neurology and Stroke
Issue number4
StatePublished - Dec 7 2015


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