TY - JOUR
T1 - Electron microscopy of Plasmodium falciparum 1. The structure of trophozoites in erythrocytes of human volunteers
AU - Ladda, R.
AU - Arnold, J.
AU - Martin, D.
N1 - Funding Information:
This is publication number 49 from the U.S. Army Research programme on malaria. The work is supported by U.S. Army Contract No. DA-49-193-MD-2545. *Present address: Department of Pediatrics, University of Washington, School of Medicine, Seattle, Washington, 98105.
PY - 1966
Y1 - 1966
N2 - Electron microphotographs of early trophozoites of Plasmodium falciparum from human volunteers were compared with those of Plasmodium berghei in the rat. Human and rodent trophozoites exhibited certain general similarities: (1) both lacked a nucleolus, (2) pigment and smooth membrane vesicles were similar, (3) both forms exhibited double limiting membranes, (4) both lacked typical mitochondial forms, (5) both forms exhibited micropyle-type structures which are apparently specialized sites of absorption. Although multilaminated-membraned bodies (whorled-patterns) were present in both forms, P. falciparum differed in that these bodies appeared to be derived from the nuclear membranes; the origin of the body in P. berghei appeared to be more related to the external limiting membranes. The erythrocytic forms of P. berghei showed a great predilection for reticulocytes or younger red cells, but P. falciparum was found only in mature red cells.
AB - Electron microphotographs of early trophozoites of Plasmodium falciparum from human volunteers were compared with those of Plasmodium berghei in the rat. Human and rodent trophozoites exhibited certain general similarities: (1) both lacked a nucleolus, (2) pigment and smooth membrane vesicles were similar, (3) both forms exhibited double limiting membranes, (4) both lacked typical mitochondial forms, (5) both forms exhibited micropyle-type structures which are apparently specialized sites of absorption. Although multilaminated-membraned bodies (whorled-patterns) were present in both forms, P. falciparum differed in that these bodies appeared to be derived from the nuclear membranes; the origin of the body in P. berghei appeared to be more related to the external limiting membranes. The erythrocytic forms of P. berghei showed a great predilection for reticulocytes or younger red cells, but P. falciparum was found only in mature red cells.
UR - http://www.scopus.com/inward/record.url?scp=0013870205&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0013870205&partnerID=8YFLogxK
U2 - 10.1016/0035-9203(66)90302-6
DO - 10.1016/0035-9203(66)90302-6
M3 - Article
C2 - 5331573
AN - SCOPUS:0013870205
SN - 0035-9203
VL - 60
SP - 369
EP - 370
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
IS - 3
ER -
