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Elementary Steps in the DNA Polymerase I Reaction Pathway
F. R. Bryant
, K. A. Johnson
,
S. J. Benkovic
Chemistry
Research output
:
Contribution to journal
›
Article
›
peer-review
177
Scopus citations
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Keyphrases
DNA Polymerase
100%
Reaction Pathway
100%
Template-primer
100%
Polymerization Reaction
60%
Kcat
40%
Rate-determining Step
40%
Processive
40%
Polymerase I
40%
Isotopic Partitioning
40%
Polymerase
20%
Steady State
20%
First-order
20%
Dissociation
20%
Isomerization
20%
Phosphodiester Bond
20%
Rapid Quench
20%
Homopolymer
20%
Time Dependence
20%
Steady-state Conditions
20%
Oligo(dT)
20%
I to
20%
Koff
20%
Bond Formation
20%
Poly(dA)
20%
Escherichia Coli DNA
20%
Rapid Equilibrium
20%
Catalytic Cycle
20%
Bond-forming
20%
Pre-steady State
20%
Biochemistry, Genetics and Molecular Biology
DNA Template
100%
DNA Polymerase I
100%
Polymerase
60%
Steady State
60%
Turnover Number
40%
Escherichia coli
20%
Enzyme
20%
Phosphodiester Bond
20%
Dissociation Rate Constant
20%
Association Rate Constant
20%
Isomerization
20%