Elevated risk of dyspnea in adults with obesity

Josh T. Goh, Bryce N. Balmain, Daniel P. Wilhite, Jorge Granados, Lydia L. Sandy, Yu Lun Liu, James A. Pawelczyk, Tony G. Babb

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


We investigated whether older adults (OA) with obesity are more likely to have dyspnea compared with OA without obesity, and whether OA with obesity are at a greater risk of having dyspnea compared with middle-aged (MA) and younger adults (YA) with obesity. We obtained de-identified data from the TriNetX UT Southwestern Medical Center database. We identified obesity and dyspnea using ICD-10-CM codes E66 and R06.0, respectively. Patients were separated into three age groups: OA, (65–75 y.o.), MA (45–55 y.o.), and YA (25–35 y.o). Within these groups, those with and without obesity or dyspnea were identified for analysis. The risk of dyspnea was greater in OA (risk ratio: 3.64), MA (risk ratio: 3.52), and YA (risk ratio: 2.76) with obesity compared with age-matched patients without obesity (all p < 0.01). The risk of dyspnea was greater in OA and MA with obesity compared with YA with obesity (both p < 0.001 vs. YA). These findings suggest that clinicians should consider obesity as an independent risk factor for dyspnea.

Original languageEnglish (US)
Article number104151
JournalRespiratory Physiology and Neurobiology
StatePublished - Dec 2023

All Science Journal Classification (ASJC) codes

  • General Neuroscience
  • Physiology
  • Pulmonary and Respiratory Medicine

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