Enantioselective reduction of β-keto esters

Douglass F. Taber; Lee J. Silverberg

doi:10.1016/S0040-4039(00)92134-8

Enantioselective reduction of β-keto esters

Douglass F. Taber, Lee J. Silverberg

Penn State Schuylkill

Research output: Contribution to journal › Article › peer-review

120 Scopus citations

Abstract

Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H₂ and 80°, using a Parr shaker. A simplified preparation of the BINAP-Ru catalyst is reported. Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H₂ and 80°, using a Parr shaker. A simplified preparation of the BINAP·Ru catalyst is reported.

Original language	English (US)
Pages (from-to)	4227-4230
Number of pages	4
Journal	Tetrahedron Letters
Volume	32
Issue number	34
DOIs	https://doi.org/10.1016/S0040-4039(00)92134-8
State	Published - 1991

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)92134-8

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title = "Enantioselective reduction of β-keto esters",

abstract = "Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H2 and 80°, using a Parr shaker. A simplified preparation of the BINAP-Ru catalyst is reported. Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H2 and 80°, using a Parr shaker. A simplified preparation of the BINAP·Ru catalyst is reported.",

author = "Taber, {Douglass F.} and Silverberg, {Lee J.}",

year = "1991",

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T1 - Enantioselective reduction of β-keto esters

AU - Taber, Douglass F.

AU - Silverberg, Lee J.

PY - 1991

Y1 - 1991

N2 - Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H2 and 80°, using a Parr shaker. A simplified preparation of the BINAP-Ru catalyst is reported. Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H2 and 80°, using a Parr shaker. A simplified preparation of the BINAP·Ru catalyst is reported.

AB - Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H2 and 80°, using a Parr shaker. A simplified preparation of the BINAP-Ru catalyst is reported. Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H2 and 80°, using a Parr shaker. A simplified preparation of the BINAP·Ru catalyst is reported.

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U2 - 10.1016/S0040-4039(00)92134-8

DO - 10.1016/S0040-4039(00)92134-8

M3 - Article

AN - SCOPUS:0025769026

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VL - 32

SP - 4227

EP - 4230

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 34

ER -

Enantioselective reduction of β-keto esters

Abstract

All Science Journal Classification (ASJC) codes

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