TY - JOUR
T1 - Endemic Visceral Leishmaniasis in a Dog from Texas
AU - Sellon, Rance K.
AU - Menard, Monica M.
AU - Meuten, Donald J.
AU - Lengerich, Eugene J.
AU - Steurer, Frank J.
AU - Breitschwerdt, Edward B.
PY - 1993/1
Y1 - 1993/1
N2 - Visceral leishmaniasis was diagnosed by cytology and positive indirect immunofluorescent antibody titers to Leishmania donovani in a 7‐month‐old female Basenji dog from Texas. Clinical and laboratory findings included weight loss, hematochezia, hyperglobulinemia, hypoalbuminemia, anemia, and neutrophilic leukocytosis. Evidence of response to treatment with diminazene aceturate and ketoconazole included improvement in the abnormal clinical, hematologic, and biochemical findings, decreased serum globulin concentration and antibody titer to Leishmania donovani, and absence of organisms in examined tissues. Several foci of endemic leishmaniasis have been reported in the United States. Because of its zoonotic potential and the lack of approved treatments for dogs with leishmaniasis in the United States, the development of effective treatment strategies is needed.
AB - Visceral leishmaniasis was diagnosed by cytology and positive indirect immunofluorescent antibody titers to Leishmania donovani in a 7‐month‐old female Basenji dog from Texas. Clinical and laboratory findings included weight loss, hematochezia, hyperglobulinemia, hypoalbuminemia, anemia, and neutrophilic leukocytosis. Evidence of response to treatment with diminazene aceturate and ketoconazole included improvement in the abnormal clinical, hematologic, and biochemical findings, decreased serum globulin concentration and antibody titer to Leishmania donovani, and absence of organisms in examined tissues. Several foci of endemic leishmaniasis have been reported in the United States. Because of its zoonotic potential and the lack of approved treatments for dogs with leishmaniasis in the United States, the development of effective treatment strategies is needed.
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U2 - 10.1111/j.1939-1676.1993.tb03163.x
DO - 10.1111/j.1939-1676.1993.tb03163.x
M3 - Article
C2 - 8455178
AN - SCOPUS:0027354532
SN - 0891-6640
VL - 7
SP - 16
EP - 19
JO - Journal of Veterinary Internal Medicine
JF - Journal of Veterinary Internal Medicine
IS - 1
ER -