Enforced CDK4 expression in a hematopoietic cell line confers resistance to the G1 arrest induced by ionizing radiation

Biochemistry, Genetics and Molecular Biology

• Bone Marrow Culture 25%
• Cell Cycle Checkpoint 25%
• Cyclin D2 25%
• Cyclin-Dependent Kinase 75%
• Ectopic Expression 25%
• G1 Phase 25%
• G1/S Transition 100%
• Kinase 25%
• P21 75%
• P53 75%
• Phosphotransferase 25%

Keyphrases

• Cyclin-dependent Kinase 2 (CDK2) 23%
• Cyclin-dependent Kinase 4 (CDK4) 100%
• Ectopic Expression 7%
• G1 Arrest 100%
• G1 Cell Cycle Arrest 7%
• Growth Inhibition 7%
• Hematopoietic Cells 7%
• Inhibitory Signaling 7%
• Ionizing Radiation 100%
• Irradiation 15%
• Kinase Activity 7%
• Myeloid Cell Lines 7%
• Overexpressing 15%
• P53 Protein 7%
• Parental Lines 7%
• Protein Level 7%
• Radiation Effects 15%
• Titration 7%

Immunology and Microbiology

• Bone Marrow Culture 25%
• Cell Cycle Checkpoint 25%
• Cell Cycle G1 Phase 25%
• Cyclin D2 25%
• Ectopic Expression 25%
• G1 Phase Cell Cycle Checkpoint 100%
• Hematopoietic Cell 25%
• Hematopoietic Cell Line 100%
• P53 75%