Enhancement of the separation selectivity of a group of polycyclic aromatic hydrocarbons using mixed cyclodextrin-modified micellar electrokinetic chromatography

B. Jiménez; D. G. Patterson; J. Grainger; Z. Liu; M. J. González; M. L. Marina

doi:10.1016/S0021-9673(97)00808-X

Enhancement of the separation selectivity of a group of polycyclic aromatic hydrocarbons using mixed cyclodextrin-modified micellar electrokinetic chromatography

B. Jiménez, D. G. Patterson, J. Grainger, Z. Liu, M. J. González, M. L. Marina

Forensic Science Program

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The separation selectivity of a group of twenty polycyclic aromatic hydrocarbons (PAHs) (including sixteen Environmental Protection Agency priority PAHs) was studied when mixtures of native β- and γ-cyclodextrins (CDs) are used as modifiers in the separation buffer in cyclodextrin-modified micellar electrokinetic chromatography. The ratio between the concentrations of β- and γ-CDs in the separation buffer as well as the total concentration was varied for various buffer concentrations. An enhancement in selectivity was obtained which enabled the separation of eighteen PAHs when using a 0.140-M borate buffer (pH 9) containing 0.100 M sodium dodecyl sulphate micelles, 0.042 M β-CD, 0.020 M γ-CD and 2.5 M urea. The correlation between the logarithm of the capacity factors of PAHs and the logarithm of their octanol-water distribution coefficients was also investigated.

Original language	English (US)
Pages (from-to)	411-418
Number of pages	8
Journal	Journal of Chromatography A
Volume	792
Issue number	1-2
DOIs	https://doi.org/10.1016/S0021-9673(97)00808-X
State	Published - Dec 19 1997

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Biochemistry
Organic Chemistry

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10.1016/S0021-9673(97)00808-X

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@article{d13deb99deca4d79b9e8f1177224ce71,

title = "Enhancement of the separation selectivity of a group of polycyclic aromatic hydrocarbons using mixed cyclodextrin-modified micellar electrokinetic chromatography",

abstract = "The separation selectivity of a group of twenty polycyclic aromatic hydrocarbons (PAHs) (including sixteen Environmental Protection Agency priority PAHs) was studied when mixtures of native β- and γ-cyclodextrins (CDs) are used as modifiers in the separation buffer in cyclodextrin-modified micellar electrokinetic chromatography. The ratio between the concentrations of β- and γ-CDs in the separation buffer as well as the total concentration was varied for various buffer concentrations. An enhancement in selectivity was obtained which enabled the separation of eighteen PAHs when using a 0.140-M borate buffer (pH 9) containing 0.100 M sodium dodecyl sulphate micelles, 0.042 M β-CD, 0.020 M γ-CD and 2.5 M urea. The correlation between the logarithm of the capacity factors of PAHs and the logarithm of their octanol-water distribution coefficients was also investigated.",

author = "B. Jim{\'e}nez and Patterson, {D. G.} and J. Grainger and Z. Liu and Gonz{\'a}lez, {M. J.} and Marina, {M. L.}",

note = "Funding Information: Dr. B. Jim{\'e}nez thanks the Comunidad Aut{\'o}noma de Madrid (Spain) for funding, CDC, Atlanta, GA, USA for allowing her to work at Dioxin and Related Compounds Laboratory initiating her on this subject and also University of Alcal{\'a} de Henares where this work was performed. Dr. M. L. Marina thanks the DGICYT (Spain) for project PB94-0356. ",

year = "1997",

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doi = "10.1016/S0021-9673(97)00808-X",

language = "English (US)",

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T1 - Enhancement of the separation selectivity of a group of polycyclic aromatic hydrocarbons using mixed cyclodextrin-modified micellar electrokinetic chromatography

AU - Jiménez, B.

AU - Patterson, D. G.

AU - Grainger, J.

AU - Liu, Z.

AU - González, M. J.

AU - Marina, M. L.

N1 - Funding Information: Dr. B. Jiménez thanks the Comunidad Autónoma de Madrid (Spain) for funding, CDC, Atlanta, GA, USA for allowing her to work at Dioxin and Related Compounds Laboratory initiating her on this subject and also University of Alcalá de Henares where this work was performed. Dr. M. L. Marina thanks the DGICYT (Spain) for project PB94-0356.

PY - 1997/12/19

Y1 - 1997/12/19

N2 - The separation selectivity of a group of twenty polycyclic aromatic hydrocarbons (PAHs) (including sixteen Environmental Protection Agency priority PAHs) was studied when mixtures of native β- and γ-cyclodextrins (CDs) are used as modifiers in the separation buffer in cyclodextrin-modified micellar electrokinetic chromatography. The ratio between the concentrations of β- and γ-CDs in the separation buffer as well as the total concentration was varied for various buffer concentrations. An enhancement in selectivity was obtained which enabled the separation of eighteen PAHs when using a 0.140-M borate buffer (pH 9) containing 0.100 M sodium dodecyl sulphate micelles, 0.042 M β-CD, 0.020 M γ-CD and 2.5 M urea. The correlation between the logarithm of the capacity factors of PAHs and the logarithm of their octanol-water distribution coefficients was also investigated.

AB - The separation selectivity of a group of twenty polycyclic aromatic hydrocarbons (PAHs) (including sixteen Environmental Protection Agency priority PAHs) was studied when mixtures of native β- and γ-cyclodextrins (CDs) are used as modifiers in the separation buffer in cyclodextrin-modified micellar electrokinetic chromatography. The ratio between the concentrations of β- and γ-CDs in the separation buffer as well as the total concentration was varied for various buffer concentrations. An enhancement in selectivity was obtained which enabled the separation of eighteen PAHs when using a 0.140-M borate buffer (pH 9) containing 0.100 M sodium dodecyl sulphate micelles, 0.042 M β-CD, 0.020 M γ-CD and 2.5 M urea. The correlation between the logarithm of the capacity factors of PAHs and the logarithm of their octanol-water distribution coefficients was also investigated.

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Enhancement of the separation selectivity of a group of polycyclic aromatic hydrocarbons using mixed cyclodextrin-modified micellar electrokinetic chromatography

Abstract

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