Epinephrine is associated with both erectile dysfunction and lower urinary tract symptoms

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5 Scopus citations


Objective: To determine whether patients with erectile dysfunction (ED) have a higher incidence of insulin resistance (IR) when compared with controls. Design: Prospective case-control study. Setting: Academic medical center. Patient(s): Twenty-nine nondiabetic men aged 18-66 years were enrolled. Of these, 28 completed the study: 17 had ED, and 11 did not. Intervention(s): Validated ED questionnaires, examination, serum hormones evaluation, and oral glucose tolerance testing. Main Outcome Measure(s): Association of IR with ED. Result(s): The association between worsening degrees of both lower urinary tract symptoms (LUTS) and ED was reaffirmed, as was a potential correlation between the two-epinephrine. There was a negative association between serum levels of epinephrine and scores on the 5-item version of the International Index of Erectile Dysfunction for ED (Spearman correlation coefficient = -0.38). On the other hand, men with ED were not more likely to have IR compared with controls. Conclusion(s): Epinephrine may be the common link between ED and LUTS.

Original languageEnglish (US)
Pages (from-to)837-842
Number of pages6
JournalFertility and sterility
Issue number3
StatePublished - Feb 2010

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology


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