Er+ breast cancer strongly depends on mcl-1 and bcl-xl anti-apoptotic proteins

Keyphrases

• Estrogen Receptor 100%
• Myeloid Cell leukemia-1 (Mcl-1) 100%
• Anti-apoptotic Proteins 100%
• ER+ Breast Cancer 100%
• Breast Cancer 66%
• Cancer Types 66%
• BH3 Mimetics 66%
• New Treatment Options 33%
• Adaptation 33%
• Breast Cancer Cells 33%
• Effective Treatment 33%
• Cancer Cells 33%
• Cytotoxicity 33%
• Rapid Development 33%
• Treatment Outcome 33%
• Bcl-xL 33%
• Net Change 33%
• Therapeutic Potential 33%
• Potential Therapy 33%
• Estrogen Receptor-positive 33%
• Anti-apoptotic 33%
• Breast Tumor 33%
• Acquired Resistance 33%
• Cancer Cell Resistance 33%
• Causes of Mortality 33%
• Clinical Relapse 33%
• Dual Inhibition 33%
• Resistance to Therapy 33%
• Therapeutic Combinations 33%
• AKT Inhibitor 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Ipatasertib 20%
• BIM Protein 20%