Eradication of human medulloblastoma tumor xenografts with a combination of O⁶-benzyl-2'-deoxyguanosine and 1,3-bis(2-chloroethyl)-1-nitrosourea

Keyphrases

• Benzyl 100%
• Nitrosourea 100%
• Tumor Xenograft 100%
• 2′-Deoxyguanosine 100%
• Medulloblastoma 100%
• 1,3-bis(2-chloroethyl)-1-nitrosourea 100%
• Methylguanine Methyltransferase 50%
• DNA Methyltransferase Inhibitor 25%
• Therapeutic Effect 25%
• Athymic Mice 25%
• Clinical Trials 12%
• Tumor 12%
• Inflammation 12%
• Water-soluble 12%
• High Dose 12%
• Central Nervous System 12%
• Maximum Tolerated Dose 12%
• O6-methylguanine-DNA Methyltransferase 12%
• O6-methylguanine 12%
• Edema 12%
• Tumor Suppression 12%
• Potentiation 12%
• Optimal Dose 12%
• Brain Tumor 12%
• Dosage Adjustment 12%
• Central Nervous System Tumors 12%
• Bowel Wall 12%
• DNA Methyltransferase Activity 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Neoplasm 100%
• Deoxyguanosine 100%
• Carmustine 100%
• Medulloblastoma 100%
• Nude Mouse 20%
• DNA Methyltransferase 20%
• DNA Methyltransferase Inhibitor 20%
• Therapeutic Effect 20%
• Malignant Neoplasm 10%
• Clinical Trial 10%
• Inflammation 10%
• Bleeding 10%
• Cancer Inhibition 10%
• Edema 10%
• Combination Drug 10%
• Methylated DNA Protein Cysteine Methyltransferase 10%
• Central Nervous System Tumor 10%
• Intracranial Tumor 10%
• 6 O Benzylguanine 10%