Erratum: The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans (PLoS Pathogens (2021) 17:4 (e1009350) DOI: 10.1371/journal.ppat.1009350)

Eillen Tecle, Crystal B. Chhan, Latisha Franklin, Ryan S. Underwood, Wendy Hanna-Rose, Emily R. Troemel

Research output: Contribution to journalComment/debatepeer-review

Abstract

After publication of this article, the authors noted an error in the amino acid change predicted for the pnp-1(jy90) mutant allele. The mutant allele is incorrectly annotated as Leucine throughout the text. The wild-type codon is TCC, which codes for the amino acid Serine, and the correct jy90 mutant allele is TTC, which codes for the amino acid Phenylalanine. The PLOS Pathogens editors have confirmed that this error does not affect the conclusions of the study. Fig 1 is incorrect due to the error described above. The authors have provided a corrected version here. (Figure Presented) here. In the pnp-1 is a negative regulator of IPR gene expression subsection of the Results, there is an error in the fourth sentence of the first paragraph. The correct sentence is: From this analysis, we identified a missense mutation in the PNP gene pnp-1, which should result in substitution of a conserved serine (S51 or S68 in isoform a or b, respectively) to phenylalanine. There is an error in the sixth sentence of the fifth paragraph of the Discussion. The correct sentence is: Support for the model that the catalytic activity of pnp-1 is required for its effects on the IPR comes from the pnp-1(jy90) allele, which has a conserved serine mutated to phenylalanine.

Original languageEnglish (US)
Article numbere1010699
JournalPLoS pathogens
Volume18
Issue number7
DOIs
StatePublished - Jul 2022

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Microbiology
  • Immunology
  • Molecular Biology
  • Genetics
  • Virology

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