TY - JOUR
T1 - Eruptive latent metastatic melanomas after initiation of antitumor necrosis factor therapies
AU - Fulchiero, Gregory J.
AU - Salvaggio, Heather
AU - Drabick, Joseph J.
AU - Staveley-O'Carroll, Kevin
AU - Billingsley, Elizabeth M.
AU - Marks, James G.
AU - Helm, Klaus F.
PY - 2007/5/1
Y1 - 2007/5/1
N2 - We report two cases of late recurrence of eruptive locoregional metastatic melanoma occurring 6 and 9 years after definitive surgical treatment. Each case (stage IB and IA) occurred after initiation of the subcutaneous anti-tumor necrosis factor medications etanercept and adalimumab, respectively. We discuss the association of immune suppression and melanoma. These cases illustrate a previously unrecognized and potentially causal relationship between tumor necrosis factor-α inhibition and reactivation of latent melanoma.
AB - We report two cases of late recurrence of eruptive locoregional metastatic melanoma occurring 6 and 9 years after definitive surgical treatment. Each case (stage IB and IA) occurred after initiation of the subcutaneous anti-tumor necrosis factor medications etanercept and adalimumab, respectively. We discuss the association of immune suppression and melanoma. These cases illustrate a previously unrecognized and potentially causal relationship between tumor necrosis factor-α inhibition and reactivation of latent melanoma.
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U2 - 10.1016/j.jaad.2006.12.024
DO - 10.1016/j.jaad.2006.12.024
M3 - Article
C2 - 17434043
AN - SCOPUS:34047254327
SN - 0190-9622
VL - 56
SP - S65-S67
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 5 SUPPL.
ER -