Abstract
A carbon fiber microelectrode is shown to give a potential-dependent dopamine-selective response in rat brain tissue. However, distinct evidence for dopamine release is not obtained with intraperitoneal amphetamine administration (1.8 or 3.7 mg · kg-1). In rats which habe been unilaterally depleted of dopamine, the change in electrochemical signal obtained in the lesioned striatum is very similar to that measured on the non-lesioned side following amphetamine administration. This indicates that substances other than dopamine contribute to the observed signals.
Original language | English (US) |
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Pages (from-to) | 141-144 |
Number of pages | 4 |
Journal | European Journal of Pharmacology |
Volume | 75 |
Issue number | 2-3 |
DOIs | |
State | Published - Oct 22 1981 |
All Science Journal Classification (ASJC) codes
- Pharmacology