Abstract
Congenic lines B10.KPA42, B10.KPA132, B10.SNA57, B10.DRB62, and B10.WOA105 carry H-2 haplotypes of wild mice on the genetic background of the strain C57BL/10Sn. Two of the lines (B10.DRB62 and B10.WOA105) have H-2 haplotypes indistinguishable from H-2(v) of B.10SM. The H-2 haplotype of one line (B10.SNA57) seems to have arisen from H-2(v) by recombination between the D and Qa-2 loci. The H-2 haplotypes of the remaining two lines probably arose from H-2(v) by recombination between the C4 and D loci. Since all six and no other lines carry the rare Neu-1(a) allele, the neuraminidase-1 locus is probably located proximal to the H-2D locus. Typing of H-2(s) recombinants for the enzyme acid phosphatase liver, the processing of which is controlled by the Neu-1 locus, suggests that the locus resides between the E(α) and D loci, that is in the S region.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2089-2093 |
| Number of pages | 5 |
| Journal | Journal of Immunology |
| Volume | 129 |
| Issue number | 5 |
| State | Published - 1982 |
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Immunology