Expanded review criteria: The case of nonpharmacological interventions in Dementia

Jiska Cohen-Mansfield, Kathleen Buckwalter, Elizabeth Beattie, Karen Rose, Christine Neville, Ann Kolanowski

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


This paper challenges the assumptions underlying many reviews and offers alternative criteria for examining evidence for nonpharmacological interventions. We evaluated 27 reviews examining interventions for persons with dementia as they relate to the issues of selection based on randomized controlled trial (RCT) design. Reviews were described by type of intervention, level of cognitive function, and criteria for inclusion. Of the 27 reviews, 46% required RCTs for inclusion and most had stringent inclusion criteria. This resulted in poor utilization of the literature and low ecological validity. Eliminating most of the available data poses a critical problem to clinical and research development. Studies meeting strict methodological criteria may not generalize to the greater population or may exclude sub-populations and interventions. Limitations of double-blind RCTs and potential design solutions are set forth based on appropriate populations, problems, interventions, and settings characteristics.

Original languageEnglish (US)
Pages (from-to)15-28
Number of pages14
JournalJournal of Alzheimer's Disease
Issue number1
StatePublished - 2014

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Clinical Psychology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health


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