Experimental Evaluation of a Surface Charge Method for Computing the Induced Magnetic Field in Trabecular Bone

Scott N. Hwang; Felix W. Wehrli

doi:10.1006/jmre.1999.1744

Experimental Evaluation of a Surface Charge Method for Computing the Induced Magnetic Field in Trabecular Bone

Scott N. Hwang, Felix W. Wehrli

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Abstract

The magnetic field induced in the pores of trabecular bone as a result of the susceptibility difference between bone and bone marrow was computed with the aid of magnetic surface charge models generated from images of trabecular bone specimens acquired at 78 and 63 μm resolution. The predicted field was compared with the values derived from 2D and 3D field maps obtained by echo-offset imaging techniques and excellent agreement was found between the two methods. Finally, from the slopes of regression between the experimental and computed fields, the absolute susceptibility of bone was nondestructively determined as -11.0 × 10^-6 (MKS), which is in close agreement with a reported value of -11.3 × 10^-6 obtained with powdered bone by means of a spectroscopic susceptibility matching technique (J. A. Hopkins and F. W. Wehrli, Magn. Reson. Med. 37, 494-500 (1997)).

Original language	English (US)
Pages (from-to)	35-45
Number of pages	11
Journal	Journal of Magnetic Resonance
Volume	139
Issue number	1
DOIs	https://doi.org/10.1006/jmre.1999.1744
State	Published - Jul 1999

All Science Journal Classification (ASJC) codes

Biophysics
Biochemistry
Nuclear and High Energy Physics
Condensed Matter Physics

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10.1006/jmre.1999.1744

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@article{37803daff1e14ac29c0f350766c3b5d5,

title = "Experimental Evaluation of a Surface Charge Method for Computing the Induced Magnetic Field in Trabecular Bone",

abstract = "The magnetic field induced in the pores of trabecular bone as a result of the susceptibility difference between bone and bone marrow was computed with the aid of magnetic surface charge models generated from images of trabecular bone specimens acquired at 78 and 63 μm resolution. The predicted field was compared with the values derived from 2D and 3D field maps obtained by echo-offset imaging techniques and excellent agreement was found between the two methods. Finally, from the slopes of regression between the experimental and computed fields, the absolute susceptibility of bone was nondestructively determined as -11.0 × 10-6 (MKS), which is in close agreement with a reported value of -11.3 × 10-6 obtained with powdered bone by means of a spectroscopic susceptibility matching technique (J. A. Hopkins and F. W. Wehrli, Magn. Reson. Med. 37, 494-500 (1997)).",

author = "Hwang, {Scott N.} and Wehrli, {Felix W.}",

note = "Funding Information: The authors gratefully acknowledge the assistance and expertise provided by Dr. Suzanne Wehrli in performing the NMR experiments and Dr. M. Taka-hashi for the acquisition of the rabbit specimen images. This work was supported by NIH Grants RO1 40671 and RO1 41443.",

year = "1999",

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AU - Hwang, Scott N.

AU - Wehrli, Felix W.

N1 - Funding Information: The authors gratefully acknowledge the assistance and expertise provided by Dr. Suzanne Wehrli in performing the NMR experiments and Dr. M. Taka-hashi for the acquisition of the rabbit specimen images. This work was supported by NIH Grants RO1 40671 and RO1 41443.

PY - 1999/7

Y1 - 1999/7

N2 - The magnetic field induced in the pores of trabecular bone as a result of the susceptibility difference between bone and bone marrow was computed with the aid of magnetic surface charge models generated from images of trabecular bone specimens acquired at 78 and 63 μm resolution. The predicted field was compared with the values derived from 2D and 3D field maps obtained by echo-offset imaging techniques and excellent agreement was found between the two methods. Finally, from the slopes of regression between the experimental and computed fields, the absolute susceptibility of bone was nondestructively determined as -11.0 × 10-6 (MKS), which is in close agreement with a reported value of -11.3 × 10-6 obtained with powdered bone by means of a spectroscopic susceptibility matching technique (J. A. Hopkins and F. W. Wehrli, Magn. Reson. Med. 37, 494-500 (1997)).

AB - The magnetic field induced in the pores of trabecular bone as a result of the susceptibility difference between bone and bone marrow was computed with the aid of magnetic surface charge models generated from images of trabecular bone specimens acquired at 78 and 63 μm resolution. The predicted field was compared with the values derived from 2D and 3D field maps obtained by echo-offset imaging techniques and excellent agreement was found between the two methods. Finally, from the slopes of regression between the experimental and computed fields, the absolute susceptibility of bone was nondestructively determined as -11.0 × 10-6 (MKS), which is in close agreement with a reported value of -11.3 × 10-6 obtained with powdered bone by means of a spectroscopic susceptibility matching technique (J. A. Hopkins and F. W. Wehrli, Magn. Reson. Med. 37, 494-500 (1997)).

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Experimental Evaluation of a Surface Charge Method for Computing the Induced Magnetic Field in Trabecular Bone

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