TY - JOUR
T1 - Exploring the underlying genetics of craniofacial morphology through various sources of knowledge
AU - Roosenboom, Jasmien
AU - Hens, Greet
AU - Mattern, Brooke C.
AU - Shriver, Mark D.
AU - Claes, Peter
N1 - Publisher Copyright:
© 2016 Jasmien Roosenboom et al.
PY - 2016
Y1 - 2016
N2 - The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.
AB - The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.
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U2 - 10.1155/2016/3054578
DO - 10.1155/2016/3054578
M3 - Review article
C2 - 28053980
AN - SCOPUS:85008686509
SN - 2314-6133
VL - 2016
JO - BioMed Research International
JF - BioMed Research International
M1 - 3054578
ER -